A dialogue between a Zen Buddhist monk turned psychedelic psychotherapist and the neuroscientist leading USC's mindfulness research. Free. Live at USC and on Zoom.
Psychedelic-assisted therapy is the fastest-moving frontier in mental health. The FDA has granted psilocybin “Breakthrough Therapy” designation. MDMA-assisted therapy for PTSD completed Phase III trials. Oregon has legalized guided psilocybin sessions. The science is no longer theoretical — it is clinical, regulatory, and accelerating.
But here is the question almost nobody in the psychedelic research community is asking with sufficient rigor: what is the role of contemplative practice — meditation, mindfulness, non-dual awareness — in making psychedelic therapy actually work?
This event brings together two people uniquely qualified to answer that question. Dr. Rael Cahn — Soul Syndicate's scientific advisor, director of the USC Center for Mindfulness Science, and Principal Investigator on the MAPS Phase III MDMA/PTSD epigenetic study — is joined by Dr. Michael Sapiro, an ordained Zen Buddhist monk, clinical psychologist, and psychedelic psychotherapist who authored Truth Medicine: Healing and Living Authentically Through Psychedelic Psychotherapy.
This is not a lecture. It is a dialogue between a neuroscientist who measures consciousness and a monk who embodies it — exploring what happens when those two traditions converge in a therapeutic setting.
Limited in-person seats. Virtual access available worldwide.
Psychiatrist · Neuroscientist · Director, USC Center for Mindfulness Science
25+ years researching the neuroscience of meditation, altered states, and psychedelic-assisted therapy. Principal Investigator on the MAPS Phase III MDMA-assisted therapy for PTSD epigenetic study. Leads the Meditation and Psychedelic Therapy lab at the USC Brain and Creativity Institute. Currently running a Mindfulness-Assisted Psychedelic Therapy study.
Zen Buddhist Monk · Clinical Psychologist · Psychedelic Psychotherapist
Ordained Zen Buddhist monk turned clinical psychologist and psychedelic psychotherapist. Author of Truth Medicine: Healing and Living Authentically Through Psychedelic Psychotherapy. Fellow at the Institute of Noetic Sciences. Works with first responders and special operations veterans at the Boise Ketamine Clinic.
Most psychedelic research focuses on the compound. This conversation focuses on the container — the contemplative framework that determines whether a psychedelic experience produces lasting transformation or temporary disruption.
Non-dual awareness — the direct recognition that subject and object are not separate — is the state most frequently reported in both deep meditation and psychedelic peak experiences. What happens when a therapist can guide from that recognition?
Not theory. Practice. How do you actually integrate mindfulness into psychedelic-assisted sessions? What does the protocol look like? What changes in outcomes?
Dr. Cahn brings the neuroscience. Dr. Sapiro brings the clinical experience. Together, they address both the extraordinary potential and the real risks of this convergence.
Can't make it in person? Watch live from anywhere.
“Awakening is not a metaphor. Buddhist meditation practices produce measurable increases in basic wakefulness and alertness — a literal neurophysiological shift.”
Dr. Rael Cahn is Soul Syndicate's scientific advisor. Every research claim we publish passes through his review. His work on the epigenetics of MDMA-assisted therapy — showing that psychedelic treatment produces measurable DNA methylation changes in the stress-response gene — is featured in our investigation into inherited trauma and spiritual awakening.
His research demonstrates that “awakening” is not a metaphor — it is a literal neurophysiological shift. This event takes that finding further: what happens when psychedelic therapy is grounded not just in clinical protocol, but in the contemplative tradition that has studied consciousness for millennia?
Venue: USC Leonard Davis School of Gerontology
Address: 3715 McClintock Ave, Los Angeles, CA 90089
Doors: 5:50 PM PT
Parking: Downey Way Structure (paid)
Price: Free
Platform: Zoom Webinar
Time: 6:00 PM – 7:30 PM PT
Access: Link sent after registration
Price: Free
March 26, 2026 · 6:00 PM PT · USC Campus or Zoom
Free
Presented by the USC Center for Mindfulness Science · Promoted by Soul Syndicate
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